Elsewhere, Man City have been paired with Villarreal and Bayern Munich will tackle Atletico Madrid in a heavyweight encounter
Manchester United will take on Paris Saint-Germain in the last 16 of the 2021-22 Champions League, while Liverpool face Red Bull Salzburg and holders Chelsea must overcome Lille in order to keep the defence of their crown on track.
Elsewhere, Real Madrid have their sights set on claiming the scalp of Benfica and Manchester City tackle Villarreal.
Bayern Munich face a tough test against Atletico Madrid, Inter will try to contain free-scoring Ajax and Sporting meet Juventus.
Champions League last-16 draw in full
Benfica vs Real Madrid
Villarreal vs Manchester City
Atletico Madrid vs Bayern Munich
Red Bull Salzburg vs Liverpool
Inter vs Ajax
Sporting vs Juventus
Chelsea vs Lille
PSG vs Manchester United
