Last night defeat is Rangnick’s first since he took charge, and his team needs to learn their lessons.
Going forward, they looked lost for most of the game, and they need to work on their game to qualify for the Champions League this season.
Wolves are now three points behind United and up to eighth in the Premier League table.
Thanks to Moutinho’s second-half strike, Wolves have secured their first league win at Old Trafford since 1980.
Lage’s men were the better team throughout the 90 minutes, with De Gea keeping the likes of Semedo, Podence and Neves at bay in the first half.
United improved for 10 or 15 minutes in the second half, but it was not enough as Moutinho secured all three points with eight minutes of normal time remaining.
After Traore’s cross was cleared, the Wolves midfielder collected the ball and fired past De Gea to reward Wolves’ travelling supporters.